Module 9.6b et c Recombinant antibodies and immunotherapy

Objectives

Design, development and production of recombinant antibodies.

Program and content of the module

Theoretical courses : 20h

  • Molecular evolution of recombinant antibodies.
  • From camelids to medicines: next-generation therapeutic antibodies ?
  • Selection and therapeutic potential of non-human primates antibodies targeting a bacterial toxin.
  • Optimisation of monoclonal therapeutic antibodies: from bench to bedside.
  • Anti-toxins recombinant antibodies. New antibody formats and therapeutic or diagnostic potential.
  • Rabies and actual treatments: potential of recombinant antibodies.

Tutorials : 10h

  • Critical analysis of English written scientific publications in relation with programs of UE 9.1, 9.2, 9.4, 9.6, 9.7, 9.8 et 9.9.
  • Fifteen minutes oral presentation (pair working) of a scientific publication followed by 15 minutes of questions by the jury and other students of the track.