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Ecouter

Module 9.8a Endosymbiogenesis and evolution, transgenesis

Objectives

To understand that micro-organisms are not necessarily pathogens.

Program : 20h theoretical courses and 10h tutorials

  • Risks and stakes of gene therapy.
  • Development of virus-derived vectors.
  • Immune response during gene therapy.
  • Control of gene expression.
  • Molecular basis of RNA interference.
  • Transgenesis models in large animals, nematodes and plants.
  • Diversity and evolution of gut microbial communities in insects.
  • Transposon-derived neogenes in humans.
  • Endogenous retro-elements and placenta differenciation.
  • Viruses adaptation.
  • Endosymbiogenesis and polydnaviruses.
  • A bacterial endosymbiont (Wolbachia): evolutionnary consequences of an intracellular life style.
  • Symbiosis and immunity in Arthropods.