Module 9.8b Adjuvants and modulation of the immune response


  • Presentation of the different adjuvant types on the market and in development.
  • Criteria for the choice of an adjuvant.
  • Micro and nano-technologies and vaccine strategy.

Methodological and technical skills acquired

Different types of adjuvant, types of immune response to promote, criteria for selection of adjuvant.

Program : 20h theoretical courses 10h tutorials

  • General knowledge on adjuvants, types of adjuvants (E. coli labile toxin mutants, oil- and surfactant-based adjuvants).
  • Targeting innate immune receptors, ligands TLR (flagellin), TLRs and intestinal cells.
  • Delivery adjuvants: liposomes, nano-particles, particle-based synthetic ligands.
  • Routes of immunization: sublingual and transcutaneous routes.